SCIENTIFIC CONSULTANT
NEMA RESEARCH
ESTERO, Florida
Prior to joining NEMA, my research focuseD resided in metabolism, physiology, genetics, and the health implications across the life course. As a dietitian, a research scientist, and academician my early career was focused on the paradigm in which we search for healthy aging by enhancing the understanding of pediatric origins of disease by interrogation metabolic processes over early development. Thus, the focus of my initial academic research resides in the nutritional biochemistry applications by which chronic disease progression could be delayed or even prevented through optimizing nutrient delivery, enhancing beneficial multi-organ crosstalk, strengthening of the musculoskeletal system, and reducing exposures to environmental contaminants early in the life course. In age-related neurodegenerative diseases like Alzheimer's and Parkinson's, protein aggregates such as amyloid-beta and alpha-synuclein accumulate, contributing to disease progression. Neuroendocrine feedback, plays a crucial role in autophagy, when dysfunctional impair autophagy, contributing to the accumulation of toxic protein aggregates in neurodegenerative diseases. Similar lipid dysregulation is observed in age-related neurodegenerative diseases and can impact membrane integrity, organelle function, and cellular signaling pathways, including dysregulated clearance of damaged mitochondria, contributing to oxidative stress and energy depletion. Collectively, the crossroads of my scientific research interests have enlightened opportunities to work to develop strategies aimed at enhancing neuronal circuitry and clearing protein aggregates to have significant impact.
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